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Biochemistry and Drug Development

Biochemistry, sometimes known as natural hormones, is the study of chemical processes in living creatures. Most hormones deal with the components, functions and relationships of cellular components such as essential proteins, sugars, fats, nucleic chemicals and other biomolecules. Among the multitude of different bio-molecules, many are complex and large substances called bio-polymers, which are made up of similar subunits called monomers.

Drug development is a catchphrase used to describe the process of bringing a new drug to industry after the causative substance has been identified through the drug development process. It includes preclinical research (microorganisms/animals) and numerous studies (in humans) and may consist of the step of obtaining regulatory approval to promote the drug.

After rapid public and economic development, more and more people have gained access to sufficient knowledge and awareness of the importance of chemistry for individual health. Because of this trend, more and more people have the interest and insight to study and think about the pathological processes and treatment of human diseases, especially those high-frequency diseases with a large public economic impact, such as heart disease, most cancers , infectious diseases, metabolic conditions, etc.

In fact, many drugs used in current clinical practice target either metabolic pathways or signaling pathways that control metabolic processes. For example, aspirin has been used as a pain reliever, nonsteroidal anti-inflammatory drug, and anticoagulant to prevent heart disorders. These pharmacological programs depend on its inhibitory effect on the oxygenation activity necessary for the biosynthesis of prostaglandins.

In addition, new therapies in development, such as histone acetylene inhibitors, also focus on solid biochemical fundamentals. Finally, the side effects, level of resistance, biotransformation, and toe-tips of medication in the human system also involve complex biochemical processes.

Therefore, all these biochemical processes, the regulatory systems of the mobile metabolic rate, the changes of metabolic processes under pathological statements and the causes of these metabolic changes associated with the disease become important topics of interest not only for scientists, health experts and drug designers , but also for the sufferers. , upcoming experts and regular visitors.

In addition to small molecule drug therapy, new techniques such as bioengineering and gene therapies are being developed to control the condition. Although these new treatment techniques are seemingly not directly related to chemistry, in fact, chemistry is still the basis for the focus on identification, focus on approval, bioengineering processes and control of the concept of transgenes in the case of gene treatments.

The completion of the human genome project not only accelerated the speed of biochemical discoveries and drug development, but also revealed the unexpected fact that many gene products have not been functionally or biochemically identified and that many aspects of basic cell metabolism, particularly under various diseases , remain unclear.

Consequently, the metagenomic era is becoming a golden age for biochemical research, drug discovery focus, and drug development. This growing body of knowledge for all your customers becomes a new challenge, the combination of digital handling, Internet technology and Open Access policy provides an ideal way to meet this task.

For more information, you can see the list of chemical journals.

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